Detalhe da pesquisa
1.
A Phase 1 study of the long-acting anti-IL-5 monoclonal antibody GSK3511294 in patients with asthma.
Br J Clin Pharmacol
; 88(2): 702-712, 2022 02.
Artigo
Inglês
| MEDLINE | ID: mdl-34292606
2.
A nebulised antitumour necrosis factor receptor-1 domain antibody in patients at risk of postoperative lung injury: A randomised, placebo-controlled pilot study.
Eur J Anaesthesiol
; 37(11): 1014-1024, 2020 11.
Artigo
Inglês
| MEDLINE | ID: mdl-32467417
3.
A pilot clinical trial of recombinant human angiotensin-converting enzyme 2 in acute respiratory distress syndrome.
Crit Care
; 21(1): 234, 2017 09 07.
Artigo
Inglês
| MEDLINE | ID: mdl-28877748
4.
Characterisation of the clinical and activated T cell response to repeat delayed-type hypersensitivity skin challenges in human subjects, with KLH and PPD, as a potential model to test T cell-targeted therapies.
Inflamm Res
; 65(5): 389-404, 2016 May.
Artigo
Inglês
| MEDLINE | ID: mdl-26969026
5.
A Randomized Dose-Escalation Study of the Safety and Anti-Inflammatory Activity of the p38 Mitogen-Activated Protein Kinase Inhibitor Dilmapimod in Severe Trauma Subjects at Risk for Acute Respiratory Distress Syndrome.
Crit Care Med
; 43(9): 1859-69, 2015 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-26102252
6.
Clinical efficacy and tolerability of a novel selective corticosteroid in atopic dermatitis--two randomised controlled trials.
Skin Pharmacol Physiol
; 28(3): 159-66, 2015.
Artigo
Inglês
| MEDLINE | ID: mdl-25614148
7.
Efficacy and safety of once-daily GW870086 a novel selective glucocorticoid in mild-moderate asthmatics: a randomised, two-way crossover, controlled clinical trial.
J Asthma
; 50(10): 1077-82, 2013 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-23991670
8.
Effect of severe renal impairment on umeclidinium and umeclidinium/vilanterol pharmacokinetics and safety: a single-blind, nonrandomized study.
Int J Chron Obstruct Pulmon Dis
; 10: 15-23, 2015.
Artigo
Inglês
| MEDLINE | ID: mdl-25565796
9.
Effects of moderate hepatic impairment on the pharmacokinetic properties and tolerability of umeclidinium and vilanterol in inhalational umeclidinium monotherapy and umeclidinium/vilanterol combination therapy: an open-label, nonrandomized study.
Clin Ther
; 36(7): 1016-1027.e2, 2014 Jul 01.
Artigo
Inglês
| MEDLINE | ID: mdl-24947493
10.
Safety, tolerability, pharmacokinetics and pharmacodynamics of single and repeat inhaled doses of umeclidinium in healthy subjects: two randomized studies.
Clin Drug Investig
; 33(7): 477-88, 2013 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-23784369
11.
Influence of renal and hepatic impairment on the pharmacokinetic and pharmacodynamic properties and tolerability of fluticasone furoate and vilanterol in combination.
Clin Ther
; 34(12): 2316-32, 2012 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-23200625